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6-Monoacetylmorphine (6-MAM) Confirmation, Urine

Additional Codes

Primary ID

SQ Code

Epic Code

MayoAccess ID

Mayo Test ID


6MAMU Reflex Order Only 6MAMU 6MAMU

Reporting Name

6-MAM Confirmation, U

Useful For

Determination of heroin use

Method Name

Gas Chromatography-Mass Spectrometry (GC-MS)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type


Advisory Information

1. If urine creatinine is required or adulteration of the sample is suspected, order ADULT / Adulterants Survey, Urine.

2. For chain-of-custody testing, order 6MAMX / 6-Monoacetylmorphine (6-MAM), Chain of Custody, Urine.

Specimen Required

Supplies: Urine Container, 60 mL (T313)

Collection Container/Tube: Plastic, 60-mL urine container (T313)

Specimen Volume: 20 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative.

Additional Information:

1. No specimen substitutions.

2. No STATS are accepted for this procedure.

Specimen Minimum Volume

2.1 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 14 days
  Frozen  14 days
  Ambient  72 hours

Reject Due To


Mild OK; Gross OK




Mild OK; Gross OK



Reference Values


Cutoff concentrations:


<5 ng/mL

Day(s) and Time(s) Performed

Monday, Wednesday, Friday

CPT Code Information


G0480 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
6MAMU 6-MAM Confirmation, U 19593-3


Result ID Test Result Name Result LOINC Value
30983 6-Monoacetylmorphine by GC/MS 19593-3
29898 6-MAM Interpretation 69050-3
29899 Chain of Custody 77202-0

Specimen Retention Time

2 weeks

Analytic Time

2 days

NY State Approved


Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.