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Amphetamine-Type Stimulants Confirmation, Meconium

Important Note

This is a reflex test for lab use only.

Additional Codes

Primary ID

Epic Code

Mayo Test ID

ACMEC

REFLEX ORDER ONLY-LAB3181 AMPHM

Reporting Name

Amphetamines, Confirmation, M

Useful For

Detecting in utero exposure to amphetamine-type stimulants up to 5 months before birth

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Meconium


Ordering Guidance


For chain-of-custody testing, order AMPMX / Amphetamine-Type Stimulants Confirmation, Chain of Custody, Meconium.



Specimen Required


Supplies: Stool container, Small (Random), 4 oz (T288)

Container/Tube: Stool container

Specimen Volume: 1 g (approximately 1 teaspoon)

Collection Instructions: Collect entire random meconium specimen.


Specimen Minimum Volume

0.3 g (approximately 1/4 teaspoon)

Specimen Stability Information

Specimen Type Temperature Time Special Container
Meconium Frozen (preferred) 28 days
  Ambient  28 days
  Refrigerated  28 days

Reject Due To

Grossly bloody Reject; Pink OK
Stool
Diapers
Reject

Reference Values

Negative

Positives are reported with a quantitative liquid chromatography tandem mass spectrometry (LC-MS/MS) result.

 

Cutoff concentrations for LC-MS/MS testing:

Amphetamine: 20 ng/g

Methamphetamine: 20 ng/g

3,4-Methylenedioxyamphetamine: 20 ng/g

3,4-Methylenedioxyethylamphetamine: 20 ng/g

3,4-Methylenedioxymethamphetamine: 20 ng/g

Day(s) Performed

Monday through Sunday

CPT Code Information

80324

80359

G0480 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
AMPHM Amphetamines, Confirmation, M 69021-4

 

Result ID Test Result Name Result LOINC Value
31854 Amphetamine 43934-9
31855 Methamphetamine 69022-2
31856 3,4-methylenedioxyamphetamine 69023-0
31858 3,4-methylenedioxyethylamphetamine 69024-8
31857 3,4-methylenedioxymethamphetamine 69025-5
31882 Interpretation 69050-3
31883 Chain of Custody 77202-0

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

Report Available

2 to 3 days

Specimen Retention Time

2 weeks

NY State Approved

Yes

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.