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HelpAcetylcholine Receptor (Muscle AChR) Binding Antibody, Serum
Additional Codes
Orderable Codes:
| Epic Code | Atlas Code | Mayo Test ID | Order LOINC |
| LAB836 | ACETYC | ARBI | 97558-1 |
Result Component(s):
| Reporting Name | Epic Code | Atlas Code | Mayo Test ID | Result LOINC |
| ACh Receptor (Muscle) Binding Ab | 12301000574 | MACETY | 8338 | 97558-1 |
Reporting Name
ACh Receptor (Muscle) Binding AbUseful For
Supporting the diagnosis of autoimmune myasthenia gravis (MG) in adults and children
Distinguishing autoimmune from congenital MG in adults and children or other acquired forms of neuromuscular junction transmission disorders
An adjunct to the test for P/Q-type calcium channel binding antibodies as a diagnostic aid for Lambert-Eaton myasthenic syndrome
Testing Algorithm
This is the primary diagnostic test for myasthenia gravis.
Method Name
Radioimmunoassay (RIA)
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumOrdering Guidance
Standalone testing (this test) is recommended in certain situations.
This test should not be requested in patients who have recently received radioisotopes, therapeutically or diagnostically, because of potential assay interference. The specific waiting period before specimen collection will depend on the isotope administered, the dose given, and the clearance rate in the individual patient. Specimens will be screened for radioactivity prior to analysis. Radioactive specimens received in the laboratory will be held for 1 week and assayed if sufficiently decayed or canceled if radioactivity remains.
Specimen Required
Patient Preparation: For optimal antibody detection, specimen collection is recommended prior to initiation of immunosuppressant medication.
Supplies: Sarstedt Aliquot Tube 5 mL (T914)
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 1.5 mL
Specimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 28 days | |
| Frozen | 28 days | ||
| Ambient | 72 hours |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
Reference Values
≤0.02 nmol/L
Day(s) Performed
Monday through Sunday
CPT Code Information
86041
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| ARBI | ACh Receptor (Muscle) Binding Ab | 97558-1 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 8338 | ACh Receptor (Muscle) Binding Ab | 97558-1 |
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.Report Available
3 to 6 daysSpecimen Retention Time
28 daysNY State Approved
YesForms
If not ordering electronically, complete, print, and send a Neurology Specialty Testing Client Test Request (T732) with the specimen.