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C1 Esterase Inhibitor, Functional, Serum

Important Note

Draw at ACC Main Campus ONLY

Collection instructions:

     Red Top Only

    Immediately after collection, place tube on ice.

Shipping & Handling instructions:

     Centrifuge in refrigerated centrifuge.  Remove serum and freeze within 30 minutes of collection.

Additional Codes

Orderable Codes:

Epic Code Atlas Code Mayo Test ID Order LOINC
LAB17559 LAB17559 C1INF 48494-9

Result Component(s):

Reporting Name Epic Code Atlas Code Mayo Test ID Result LOINC
C1 Esterase Inhibitor, Functional, S. 12301019841 MC1INF C1INF 48494-9

 


Specimen Required


Patient Preparation: Fasting, preferred but not required

Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Immediately after specimen collection, place the tube on wet ice.

2. After sample has clotted on wet ice, centrifuge at 4° C and aliquot serum into a plastic vial.

3. Freeze specimen within 30 minutes of centrifugation. Sample must be placed on dry ice if not frozen immediately.

NOTE: If a refrigerated centrifuge is not available, it is acceptable to use a room temperature centrifuge, provided the specimen is kept on ice before centrifugation and immediately afterward, the serum aliquoted and frozen.


Useful For

Diagnosing hereditary angioedema

 

Monitoring response to C1 esterase inhibitor replacement therapy

Method Name

Enzyme Immunoassay (EIA)

Reporting Name

C1 Esterase Inhib, Functional, S

Specimen Type

Serum Red

Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Red Frozen 28 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus Reject
Heat-inactivated samples Reject

Reference Values

>67% normal (normal)

41-67% normal (equivocal)

<41% normal (abnormal)

Day(s) Performed

Varies

Report Available

3 to 5 days

Specimen Retention Time

14 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

83520

LOINC Code Information

Test ID Test Order Name Order LOINC Value
C1INF C1 Esterase Inhib, Functional, S 48494-9

 

Result ID Test Result Name Result LOINC Value
C1INF C1 Esterase Inhib, Functional, S 48494-9

NY State Approved

Yes