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HelpClobazam and Metabolite, Serum
Additional Codes
Orderable Codes:
| Epic Code | Atlas Code | Mayo Test ID | Order LOINC |
| LAB15399 | LAB15399 | CLOBZ | 79408-1 |
Result Component(s):
| Reporting Name | Epic Code | Atlas Code | Mayo Test ID | Result LOINC |
| Clobazam | 12301013492 | 12301013492 | 65483 | 3487-6 |
| N-desmethylclobazam | 12301013531 | 12301013531 | 92363 | 35107-2 |
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Red top (serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions:
1. Collect blood immediately before next scheduled dose.
2. Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial.
Additional Information: Trough specimens are recommended as therapeutic ranges are based on specimens collected at trough (ie, immediately before the next dose).
Useful For
Monitoring clobazam therapy
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
Clobazam and metabolite, SSpecimen Type
Serum RedSpecimen Minimum Volume
0.35 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum Red | Refrigerated (preferred) | 28 days | |
| Ambient | 28 days | ||
| Frozen | 28 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
Clobazam
Therapeutic Range: 30-300 ng/mL
N-desmethylclobazam (Norclobazam)
Therapeutic Range: 300-3,000 ng/mL
Day(s) Performed
Monday through Friday
Report Available
Same day/1 to 5 daysSpecimen Retention Time
14 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
80339 (G0480 if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| CLOBZ | Clobazam and metabolite, S | 79408-1 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 65483 | Clobazam | 3487-6 |
| 92363 | N-desmethylclobazam | 35107-2 |
NY State Approved
YesForms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.