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Test Code DIFFAD DIFFERENTIAL BLOOD COUNT-HEMATOLOGY USE ONLY

Important Note

Differential Blood Counts cannot be ordered as a stand-alone test. Must order a Complete Blood Count with Differential. Test subject to Medicare National Coverage Decision (NCD) 190.15 - Blood Counts.

When there are less than 50 cells available to count on the differential smears, we will not be reporting out the percentage of cell types or absolute counts as the accuracy and reliability of the differential is low.  A comment will be entered that states the number of cells counted and the cells that are present.  The charge for the differential will be credited.

This test is subject to reflex testing, see Laboratory Reflex Testing Policy, you have the option to decline reflex testing if you believe it is not medically necessary.  A pathologist review and written interpretation (CPT: 85060) may be generated.

Additional Codes

Primary ID

Epic Code

Mayo Access ID

DIFFAD

 Reflex order only N/A

Test Schedule / Analytical Time / Test Priority

Daily / 24 Hours / Available STAT

Method

Automated or manual with potential smear review

Instrumentation

Sysmex XN 9000

Reference Range

MALE and FEMALE

Age

 Cell Type Absolute Number - x 103
>18 Years Neutrophil 2.20 - 8.85
>18 Years Lymphocyte 1.09 - 3.30
>18 Years Monocyte 0.10 - 0.8*
>18 Years Eosinophil 0.03 - 0.61
>18 Years Basophil

0.01 - 0.11
>18 Years Immature Grans 0.00 - 0.06
>18 Years Ret 0.5 - 2.5 %

References: MCHV normal value data from Employee Health Samples - 1994  (95% confidence range) - NE-8000 cell counter

                       Males: N=49

                       Female N=64

9/3/98 adult Monocyte reference range adjusted for Gen*S (N=37)
Ranges were verified by 2012 study on the Beckman Coulter DxH 800

Section

Hematology

Performing Location

University of Vermont Medical Center

Is the UVMMC lab NY State Certified to perform this testing?  Yes/No

Yes

Test Note

If, in the opinion of the ordering provider, a blood smear needs to reviewed by a technologist for a specific reason or abnormality, please call UVM Medical Center Laboratory Customer Service (847-5121) and ask for this review. If a pathologist consultation is desired a call must be placed to UVM Medical Center Laboratory Customer Service (847-5121). A reason for the request must be provided.

 

While an automated differential will be the default method used, there are several flags related to the WBC, PLT and RBC parameters that indicate that a manual differential must be performed. A subset of these findings will be reviewed by a pathologist.