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Test Code LAB17717 APIXABAN

Important Note

Must be drawn at the ACC if the specimen cannot be run or processed and frozen within 2 hours of collection.  

Limitations:
This chromogenic anti-Xa assay calibrated with an apixaban standard can accurately determine apixaban concentration in plasma; however, the APIX Test is not specific for apixaban and will detect any anti-Xa anticoagulant medications, including unfractionated heparin, low molecular weight heparin, fondaparinux, rivaroxaban, and edoxaban. In patients transitioning between apixaban and heparin medications, the APIX Test is unable to provide specific anticoagulant drug levels.

Additional Codes

Orderable Codes:

Epic Code Atlas Code Mayo Access ID Order LOINC
LAB17717 LAB17717 FAH6202 74214-8

Result Component(s):

Reporting Name Epic Code Atlas Code Mayo Access ID Result LOINC
Apixaban 12301020433 12301020433 FAH6203 74214-8

 

Specimen Information

Container Specimen Temperature Collect Vol Submit Vol Min Vol Stability
*Blue Top Tube Plasma Frozen To fill line 1 mL  1 mL  6 months
3.5 mL Blue Top Whole Blood Ambient To fill line To fill line To fill line 2 hours
2 mL Blue Top Whole Blood Ambient To fill line To fill line To fill line 2 hours

*TUBE MUST BE FULL AT COLLECTION. Whole blood should remain at ambient temperature until processed. Refer to Coagulation Specimen Handling  prior to collection.  Double spin before freezing-see Coag Spec Processing step 3.  Submit 2 × 0.5 mL frozen plasma aliquots for this test. Draw blood in light blue top tube(s). Spin down, remove plasma, spin plasma again and  place citrate platelet-poor plasma in the required number of plastic vials (Glass vials cannot be accepted.)  Freeze specimen at ≤ -40° C if possible.  Send specimen frozen on dry ice. Each coagulation assay requested should have one tube per test.

Test Schedule / Analytical Time / Test Priority

Daily / 24 Hours / Available STAT

Method

Apixaban chromogenic anti-Xa assay 

CPT Code(s)

Description CPT  Code
Apixaban 80299

 

Instrumentation

ACL TOP

Reference Range

Therapeutic ranges have not been established.
 

 

Section

Coagulation

Performing Location

University of Vermont Medical Center

Is the UVMMC lab NY State Certified to perform this testing?  Yes/No

Yes