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HelpNeuromyelitis Optica (NMO)/Aquaporin-4-IgG Fluorescence-Activated Cell Sorting (FACS) Assay, Spinal Fluid
Additional Codes
Orderable Codes:
| Epic Code | Atlas Code | Mayo Test ID | Order LOINC |
| LAB9890 | LAB9890 | NMOFC | 46718-3 |
Result Component(s):
| Reporting Name | Epic Code | Atlas Code | Mayo Test ID | Result LOINC |
| NMO/AQP4 IgG FACS, CSF | 12301001067 | 12301001067 | 38325 | 46718-3 |
Useful For
Diagnosis of a neuromyelitis optica spectrum disorder (NMOSD)
Diagnosis of autoimmune AQP4 channelopathy
Distinguishing NMOSD from multiple sclerosis early in the course of disease
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| NMOTC | NMO/AQP4 FACS Titer, CSF | No | No |
Testing Algorithm
When the results of this assay require further evaluation, NMOTC / Neuromyelitis Optica (NMO)/Aquaporin-4-IgG Fluorescence-Activated Cell Sorting (FACS) Assay Titer, Spinal Fluid will be performed at an additional charge.
Method Name
Flow Cytometry
Reporting Name
NMO/AQP4 FACS, CSFSpecimen Type
CSFOrdering Guidance
Necessary Information
Include relevant clinical information, name, phone number, mailing address, and e-mail address (if applicable) of ordering physician.
Specimen Required
Collection Container/Tube: Sterile vial
Specimen Volume: 3 mL
Specimen Minimum Volume
2 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| CSF | Refrigerated (preferred) | 28 days | |
| Frozen | 28 days | ||
| Ambient | 72 hours |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
Negative
Day(s) Performed
Monday, Tuesday, Thursday
Report Available
5 to 8 daysSpecimen Retention Time
28 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
86053
86053-titer (if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| NMOFC | NMO/AQP4 FACS, CSF | 46718-3 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 38325 | NMO/AQP4-IgG FACS, CSF | 46718-3 |