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Porphyrins, Quantitative, Random, Urine

Additional Codes

Orderable Codes:

Epic Code Atlas Code Mayo Test ID Order LOINC
LAB15581 LAB15581 PQNRU 93707-8

Result Component(s):

Reporting Name Epic Code Atlas Code Mayo Test ID Result LOINC
Uroporphyrin, Octa 12301013636 12301013636 32332 25166-0
Heptacarboxylporphyrins 12301013637 12301013637 32333 34314-5
Hexacarboxylporphyrins 12301013638 12301013638 32334 96795-0
Pentacarboxylporphyrins 12301013639 12301013639 32335 34352-5
Coproporphyrin, Tetra 12301013640 12301013640 32336 25167-8
Porphobilinogen 12301013641 12301013641 32337 2811-8
Amniolevulinic Acid, U. 12301021334 12301021334 623039 39782-8
Interpretation 12301013642 12301013642 32338 49291-8
Reviewed By 12301021335 12301021335 623040 18771-6

 

Reporting Name

Porphyrins, QN, Random, U

Useful For

Preferred test to begin assessment for congenital erythropoietic porphyria and porphyria cutanea tarda and during symptomatic periods for acute intermittent porphyria, hereditary coproporphyria, and variegate porphyria when specimen transport will not exceed 72 hours

Testing Algorithm

The following algorithms are available:

-Porphyria (Acute) Testing Algorithm

 

-Porphyria (Cutaneous) Testing Algorithm 

 

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Urine


Ordering Guidance


This random urine test should be ordered when the specimen will reach Mayo Clinic Laboratories within 72 hours. If transportation will take longer than 72 hours, order both PQNU / Porphyrins, Quantitative, 24 Hour, Urine and ALAUR / Aminolevulinic Acid, Urine and follow collection guidelines.



Shipping Instructions


Ship specimen in amber bottle to protect from light.



Necessary Information


Include a list of medications the patient is currently taking.



Specimen Required


Patient Preparation: Patient must  not consume any alcohol for at least 24 hours before specimen collection.

Supplies: Urine Container - Amber, 60 mL (T596)

Container/Tube: Amber, 60-mL urine container

Specimen Volume: 20 to 50 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative necessary but pH must be above 5.0. If pH is below 5.0, specimen will be rejected.

3. Specimens should be protected from light and frozen immediately following collection.


Specimen Minimum Volume

15 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Frozen 72 hours LIGHT PROTECTED

Reference Values

Uroporphyrins, Octacarboxyl:

≤3.1 mcmol/mol creatinine

 

Heptacarboxylporphyrins:

≤0.9 mcmol/mol creatinine

 

Hexacarboxylporphyrins:

≤0.3 mcmol/mol creainine

 

Pentacarboxyporphyrins:

≤1.2 mcmol/mol creatinine

 

Coproporphyrin, Tetra::

≤25.0 mcmol/mol creatinine

 

Porphobilinogen:

≤0.2 mmol/mol creatinine

 

Aminolevulinic Acid

≤ 2.3 mmol/mol creatinine

Day(s) Performed

Monday through Friday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

84110-Porphobilinogen, quantitative

84120-Porphyrins, quantitation and fractionation

82135- ALA Delta Random Urine

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PQNRU Porphyrins, QN, Random, U 93707-8

 

Result ID Test Result Name Result LOINC Value
32332 Uroporphyrin, Octa 25166-0
32333 Heptacarboxylporphyrins 34314-5
32334 Hexacarboxylporphyrins 96795-0
32335 Pentacarboxylporphyrins 34352-5
32336 Coproporphyrin, Tetra 25167-8
32337 Porphobilinogen 2811-8
623039 Aminolevulinic Acid, U 39782-8
32338 Interpretation 49291-8
623040 Reviewed By 18771-6

Report Available

2 to 4 days

Specimen Retention Time

1 week

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

NY State Approved

Yes

Method Name

High-Performance Liquid Chromatography (HPLC) with Fluorometric Detection/Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)