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Syphilis Total Antibody with Reflex, Serum

Important Note

This is a reflex test for Syphilis Serology (SYPH), for lab use only.

Additional Codes

Primary ID

Epic Code

Mayo Test ID

SYPHTR

Reflex order only SYPHT


Specimen Required


Collection Container/Tube: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Useful For

Aiding in the diagnosis of recent or past Treponema pallidum infection

 

Routine prenatal screening

 

This test is not offered as a screening or confirmatory test for blood donor specimens.

 

This test is not useful for diagnosis of congenital syphilis.

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
RPRS RPR Screen w/ Reflex, S No No
RTPPA Syphilis Ab, TP-PA, S Yes, (Order TPPA) No
RRPRQ RPR Titer, S No No
SYPNB Syphilis Total Ab Bill Only 1 No, (Bill Only) No

Testing Algorithm

Total syphilis billing will be captured under SYPNB.

 

If the total syphilis result is reactive or equivocal, then rapid plasma reagin (RPR) will be performed at an additional charge.

 

If the RPR screen result is reactive, then the RPR titer will be performed at an additional charge.

 

If the RPR screen result is nonreactive, then syphilis antibody will be performed at an additional charge.

 

See Syphilis Serology Algorithm in Special Instructions.

Special Instructions

Method Name

SYPNB: Multiplex Flow Immunoassay

RPRS, RRPRQ: Flocculation/Agglutination

RTPPA: Particle Agglutination

Reporting Name

Syphilis Total Ab w/ Reflex, S

Specimen Type

Serum

Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  14 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Heat-inactivated specimen Reject

Reference Values

SYPHILIS TOTAL ANTIBODY

Nonreactive

 

RAPID PLASMA REAGIN SCREEN

Nonreactive

 

RAPID PLASMA REAGIN TITER

Negative

 

SYPHILIS ANTIBODY, Treponema pallidum-PARTICLE AGGLUTINATION

Negative

 

Reference values apply to all ages

Day(s) and Time(s) Performed

Monday through Saturday; 9 a.m.

Analytic Time

Same day/1 day

Specimen Retention Time

14 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved or is exempt by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86780

86592 (if appropriate)

86780 (if appropriate)

86593 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
SYPHT Syphilis Total Ab w/ Reflex, S 47236-5

 

Result ID Test Result Name Result LOINC Value
SYPHT Syphilis Total Ab w/ Reflex, S 47236-5

NY State Approved

Yes

Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-General Request (T239)

-Microbiology Test Request (T244)