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Voriconazole, Serum

Additional Codes

Primary ID

Epic Code

Mayo Test ID

VORI

LAB3130 VORI

Reporting Name

Voriconazole, S

Useful For

Monitoring trough levels of voriconazole is suggested in individuals with reduced liver function, individuals with CYP2C19 polymorphisms associated with poor metabolic function, patients taking other medications that affect CYP2C19 activity, and in patients experiencing potential toxicity

 

Monitoring trough levels may be reasonable in patients who are not responding optimally or have drug interactions that may decrease voriconazole levels, or to ensure adequate oral absorption

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum Red


Specimen Required


Collection Container/Tube: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 2 mL

Collection Instructions: Spin down within 2 hours of draw.


Specimen Minimum Volume

0.6 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Red Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK
 

Reference Values

1.0-5.5 mcg/mL

Trough level (ie, immediately before next dose) monitoring is recommended.

Day(s) and Time(s) Performed

Monday; 11 a.m., Tuesday through Saturday; 12 a.m. and 11 a.m., Saturday; 4 p.m., Sunday; 3 p.m.

CPT Code Information

80285

LOINC Code Information

Test ID Test Order Name Order LOINC Value
VORI Voriconazole, S 38370-3

 

Result ID Test Result Name Result LOINC Value
88698 Voriconazole, S 38370-3

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

Analytic Time

Same day/1 day

Specimen Retention Time

2 weeks

NY State Approved

Yes