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Test Code LAB9912 CHROMOSOME ANALYSIS

Important Note

See Test Note below for available probes.

Commercial payors may require preauthorization for this test.

Outside clients please use Hem path/Flow Cytometry/Genetic Laboratory Form.

Sample Types accepted:

    - Blood on patients <30 days old for Congenital Chromosome Analysis

    - Bone Marrow

    - Neoplastic blood (not recommended)

For congenital chromosome analysis testing on patients >30 days old, please order Chromosome Analysis, Congenital Disorders, Blood (LAB15319).

For products of conception testing, please order Prenatal Whole Genome Chromosomal Microarray (LAB17656).

Submission of an order for Cytogenetic testing for congenital disorders constitutes that the ordering physician has, obtained an informed consent of the patient as required by any applicable state or federal laws with respect to the test ordered, and obtained from the patient authorization permitting UVM Medical Center to report results of each test ordered directly to the ordering physician.

FISH Testing can be added to some specimens, and some FISH Testing can be done on lymph tissue specimens, see Test Note below. Call the Cytogenetics laboratory for details 847-5121 or 1-802-991-2799.

Additional Codes

Epic Code Atlas Code Mayo Access ID Order LOINC
LAB9912 N/A N/A N/A

 

Specimen Information

Container Specimen Temp Collect Vol Submit Vol Min Vol
Na Heparin Tube, Neoplastic Whole Blood Ambient 6 mL 6 mL 3 mL
Na Heparin Tube, Pediatric <30 days old Whole Blood Ambient 3 mL 3 mL 1 mL
Na Heparin or Bone Marrow Transport Media (sterile) Bone Marrow Ambient 3 mL 3 mL 0.5 mL

 

 

Test Schedule / Analytical Time / Test Priority

Whole Blood  - Monday – Saturday / 10 – 28 days / Not available STAT

Bone Marrow/Neoplastic Blood - Monday - Saturday / 7 - 21 days / Not available STAT

Method

Culture, Microscopy, Karyotype

CPT Code(s)

Description CPT Code
Cell Culture, Blood 88230
Chromosome Analysis, Blood 88262
Chromosome Intrp & Report Part B, Blood 88291
Cell Culture, Bone Marrow/Blood Neoplastic 88237
Chromosome Analysis, Bone Marrow/Blood Neoplastic: analyze 20-25 cells 88264
Chromosome Analysis, Bone Marrow/Blood Neoplastic: analyze 15-20 cells 88262
Chromosome Analysis, Bone Marrow/Blood Neoplastic: analyze <15 cells 88262 w/modifier 52
Chromosome Interpretation & Report Part B, Bone Marrow/Blood Neoplastic 88291
Cell Culture, Blood Familial Study 88230
Chromosome Analysis, Blood Familial Study 88261
Additional Cells Counted 88285
Chromosome analysis, additional karyotypes (if appropriate) 88280

 

Instrumentation

Manual Methods

Section

Cytogenetics

Performing Location

University of Vermont Medical Center

Is the UVMMC lab NY State Certified to perform this testing?  Yes/No

Yes

Test Note

FISH Testing (Fluorescence In-Situ Hybridization):

  • Fluorescent probes can be used to determine chromosomal microdeletions, duplications, translocations, and rearrangements.
  • Fluorescent probes can be used to characterize chromosome abnormalities associated with specific hematologic diseases.
  • Reporting time is 1 week.
  • FISH testing can be done on the same sample submitted for chromosome evaluation or it can be ordered alone.

A list of FISH probes orderable at UVMMC can be found under FISH Testing, Epic Code LAB9913.

LOINC Code Information

N/A